Scientists chemical synthesis of the latest antibiotics – Science and technology – People’s network brock lesnar

Scientists chemical synthesis of "new" antibiotics — technology — people.com.cn original title: scientists chemical synthesis of "new" antibiotics as the first antibiotic Washington found nearly 30 years (reporter Han Kun) recently, the Department of chemistry of University of Hong Kong associate professor Li Xuechen team and United States University of Florida, Hong Kong Polytech University researchers, research results of the model the antibiotic Teixobactin published in "nature – Communication". Teixobactin is the first new antibiotic discovered in the past 30 years, and its chemical synthesis has laid a foundation for the application and development of the new generation of antibiotics. Over the past 7 years, the Li Xuechen team has been committed to the development of new antibiotics. For the first time in 2013 years, all of them were synthesized by chemical methods of daptomycin, and on this basis, to carry out a new generation of daptomycin antimicrobial drug development work. Recently, the Li Xuechen team with chemical synthesis method, the successful synthesis of popular antibacterial compounds Teixobactin. A new antibiotic Teixobactin in 2015 by US scientists found that realized the huge breakthrough in the field of antibacterial drugs, can kill methicillin-resistant Staphylococcus aureus (MRSA), vancomycin resistant enterococci (VRE), Mycobacterium tuberculosis and other deadly pathogens. The most critical is that Teixobactin does not induce the generation of bacterial resistance. Working with a chemistry lab at the University of Central Florida, Li Xuechen’s team became one of the world’s first successful development of Teixobactin synthetic routes. Their synthetic methods based on research and development, the research team has synthesized 10 promising Teixobactin analogues (has applied to the U.S. provisional patent), they study the synthesis pathway can quickly and efficiently synthesize a variety of Teixobactin derivatives. The next two years, they will be committed to the synthesis of 100 different Teixobactin derivatives in order to improve the efficacy and clinical application. (commissioning editor Wei Yan and Zhao Zhuqing)相关的主题文章: